thanks for your note. always good to hear of other NET folks with good outcomes. I lost 5 lbs in a week. not sure about the week off the drug. Not sure if same problem will recur when I go back on. If so, the possibility of reducing dosage, or doing every other day at same 10mg. will give it a real try but it’s hard to feel so much worse with treatment than without any treatment. will start back on 3/28 and will stay connected to Mayo Connect. thanks again.