In Japan, vitamin K is prescribed at 45 mg a day. There is a calcium product, Osteo K that has that amount in it. My functional medicine doctor wants me on 22-45 mg a day. My rheumatologist said 45 mg a day was fine. So, even though that dosage is HUGE, that’s what I’m taking. I also take calcium citrate, 1000 mg, magnesium 500 mg and Vit D, 10,000 IU(my levels were extremely low).