Greetings @saltyg

I hope the combination of Embrel and prednisone is working for you. AS and PMR is a bad mix. Just so you know, my ophthalmologist wasn't convinced that Actemra was optimal treatment for uveitis.

When I first tapered off prednisone after Actemra was started, I had a flare of uveitis for the first time in nearly 12 years. Actemra was stopped while I was taking 60 mg of prednisone and Humira. The uveitis cleared up but Humira didn't seem to control things from the PMR aspect of things.

My rheumatologist said it would be impossible to control everything that was happening to me. He said I could take either Humira or Actemra but not both.

My uveitis has always responded well to high dose prednisone followed by a fast taper. I have stopped counting the number of flares of uveitis I have had. I decided Actemra worked better for me and controlled the pain. I like being off prednisone!

If uveitis flares up again, I guess I will take prednisone for a month or two. At least I won't need to take prednisone all the time.