I can only comment on my experience so far. Vulvar melanoma, 3 surgeries for removal and last path still shows in situ cells. The depth was 14mm so immunotherapy and radiation was recommended. PET AND SLN negative.
I started immunotherapy last week and start radiation in 3 weeks. Monitoring by PET scans and exams every 3 months.
This is at UCSF skin cancer and Melanoma Center. So far I’m feeling comfortable with the treatment plan.
Good luck going forward in your journey.