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Gleason 9: ADT before radiation

Prostate Cancer | Last Active: May 14, 2023 | Replies (42)

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@drj

The question is what will a second opinion produce in choices? If the 2nd opinion is to undergo a PSMA PET, and, if done and it shows no positives outside the prostate, that might favor surgery, but I actually don't think your decision changes by much.

A positive PSMA PET would, I imagine, rule out radical surgery. If a negative PSMA PET? Note: I do not know the detection limit of PSMA PET, so a negative is a good thing but does not rule out spread beyond the prostate. You will still be stuck with choosing radiation or surgery. If surgery, then you are going for a "cure", because if the disease is confined to the prostate, if you cut it out and put it in a jar, you've likely got a cure. Having said that, I think going for a cure is a better choice for a younger man. At your age, they likely will recommend radiation. My situation (3 yrs older) is similar to you in age, health, PSA, and pathology. I chose radiation six months ago based on my estimate of side effects, quality or life, and the reality of actuarial tables.

That's one opinion. What do others think?

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Replies to "The question is what will a second opinion produce in choices? If the 2nd opinion is..."

That's a well reasoned approach and one I plane to follow unless some new evidence comes to light. There are still choices and I am curious what you decided:
ADT yes or no and how long if yes?
What type of radiation? Proton Beam Therapy? Stereotactic radio surgery?
From what I read about ADT, it would turn me from a very active 83 year old, to an old man in a year. What do you think?