I too have Stage IV PanCan diagnosed October 2022. Initial CA-19-9 was 3600. Started fulfinorix treatment. Side effects were mild neuropathy and cold sensitivity. After 6 cycles CA-19-9 rose to 42000 and scans showed progression. Switched to Abrax+Gem. After 4 cycles CA-19 dropped to 1800; after 6 cycles CA-19 dropped to 821 and scans showed considerable shrinkage of tumours in Pan and Liver. Main side effects is fatigue and taste bud changes.

Prayers for your husband.