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DiscussionGleason 9: ADT before radiation
Prostate Cancer | Last Active: May 14, 2023 | Replies (42)Comment receiving replies
Replies to "I am 4+3...PSA 5.26, Biop/6 sites, on hit, 30%, grade group 3, 77 yrs old, excellent..."
The question is what will a second opinion produce in choices? If the 2nd opinion is to undergo a PSMA PET, and, if done and it shows no positives outside the prostate, that might favor surgery, but I actually don't think your decision changes by much.
A positive PSMA PET would, I imagine, rule out radical surgery. If a negative PSMA PET? Note: I do not know the detection limit of PSMA PET, so a negative is a good thing but does not rule out spread beyond the prostate. You will still be stuck with choosing radiation or surgery. If surgery, then you are going for a "cure", because if the disease is confined to the prostate, if you cut it out and put it in a jar, you've likely got a cure. Having said that, I think going for a cure is a better choice for a younger man. At your age, they likely will recommend radiation. My situation (3 yrs older) is similar to you in age, health, PSA, and pathology. I chose radiation six months ago based on my estimate of side effects, quality or life, and the reality of actuarial tables.
That's one opinion. What do others think?
Suggest getting the 2nd opinion and then decide.