My Cardiologist has asked me to go on Zetia, because I reflect High levels of HDL and LDL. MY triglycerides are good. Keep wondering if there is not a connection between High Cholesterol and Cortisol production. I'm gonna hold out on Zetia, until I talk with my Endocrinologist. I know right carotid is 55%-60% occludid, and left is 40 or 50% percent. My cardiologist says he is comfortable with that amount of blockage because it normal for a 54 yr. old. Mitral valve mild regurgitation is not a concern either. So I'll see him in a year. I'll be keeping an eye on this stuff. If my chest pain worsens, I'll need to do something. Its very mild most times now, just kinda aware that its there.