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Radiation with or without ADT

Prostate Cancer | Last Active: Jul 6 4:27pm | Replies (16)

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@michaelcharles

Rad62: My non-medical understanding is that the rising PSA treatment range is 0.2 to 0.4/0.5 for BCR, and the trend is to treat at the lower number in the range (i.e., 0.2).
My 90 day postop PSA was a disappointing 0.19, and Radiation Oncologist prescribed 4 mos of ADT together with 38 radiation treatments. Gleason 9 w/ EPE final postop path report; 72 yrs old.
Honestly, I have not seen conflicting reports from current research.
Earlier treatment tends toward better results. And combination ADT and radiation have statistically better outcomes.
Best wishes to you in the challenging arena of PCa tx.

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Replies to "Rad62: My non-medical understanding is that the rising PSA treatment range is 0.2 to 0.4/0.5 for..."

In February 2023, I finished 28 radiation treatments for BCR. I received a 6-month shot of Eligard in October 2022 so am still dealing with side effects, which I am tolerating pretty well. I was convinced of having radiation therapy with ADT after reading an article in the Lancet describing how the addition of ADT was associated with increased metatasis-free survival.

I had my RALP in March 2022. Final pathology report was 4+5 Gleason with clear margins. In June 2022, my PSA was undetectable but rose to 0.5 in Sept 2022. Had a PSMA scan in early October but no cancer was detectable. My oncologist decided to radiate the prostate fossa as well as the pelvic lymph nodes. Still dealing with urinary and bowel issues from the radiation but they are diminishing. Am hopeful for the future.