Two years after PRT, PSA started to rise from 0.1 to 4.8. Biopsy showed that prostate is clear, but PET scan shows metastasis on some bones and lymphs. Started back on Lupron and half dose of Xtandi. PSA dropped back to 0.1 over first 3 months of Lupron + Xtandi. Has remained steady for another 4 moths. Continuing with monthly blood checks. Have all the usual side effects.