Hello @jpb, like @mom23boys i was diagnosed stage 4 de nova June 2020 at 54 years old. First line of treatment was Kisqali, Anastrozole and X-geva. For 19 months I was was NED (no evidence of disease) but then It all
Started growing again (in my breast, lymph nodes and bones). From there I went on Afinitor and Exemastane but my body didn’t do well on that (had trouble breathing) so had to stop after 6 weeks. Next up was Xeloda and scan after 6 weeks showed it was also not working and the cancer was progressing.

There were a few next step options to try but I then got lucky enough to get into a clinical trial for Dato-Dxd. I have had 6 treatments now, started last November 1, and the cancer is slowly shrinking!!!!

There are many options out there especially for HR+ HER2- MBC diagnosis is very scary but there is a lot to be hopeful about. I am on A breast cancer dragon boat team and another member is also MBC since 2016, on treatment for 4 years and now NED and not any treatment for 3 years. Stay positive, stay hopeful. I know moments can be heartbreaking but work through those moments, it’s ok to feel some grief, then push forward and make plans for your future and tell your body and mind that you plan to be here for a long time!!

Reach out if there is anything I can help with!

Stay strong warrior sister!