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Slow gi motility with severe constipation
Digestive Health | Last Active: Oct 19, 2025 | Replies (129)Comment receiving replies
I suffered for almost 4 years.
Found a surgeon who did a Pyloroplasty on November 1 and I am so much better.
Linzess really made me cramp all day (was in bed a lot).
The Motegrity was even worse for me.
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Can you describe the cramping? I was taking Lubiprostone twice a day until I started having rectal cramping in left side. I’ve never had anything like it. No cramping in belly though. It hasn’t returned since I stopped the meds. Just curious. I think Lubiprostone works like Linzess.