← Return to Low Dose Naltrexone and Prednisone for PMR?

Discussion

Low Dose Naltrexone and Prednisone for PMR?

Polymyalgia Rheumatica (PMR) | Last Active: Aug 4 6:29am | Replies (85)
Comment receiving replies
@pkalkstein

I will post my experiences, probably starting next week. Meanwhile, have you tried taking part of your dose at 2 AM? That cut my pain to almost nothing. Apparently doing that heads off the cytokine rush that happens from 4-4:30, or so I read.

Jump to this post

Replies to "I will post my experiences, probably starting next week. Meanwhile, have you tried taking part of..."
cambrose | @cambrose | Mar 12, 2023

This was very helpful. I had tapered down to a low dose 2.5mg prednisone for six months with some stiffness/achiness that was manageable. I went up to 3.75 when it seemed to increase/worsen this winter. After reading your comments I have been that dose at 3-4 am and noticed much improvement. My mornings are much better with this timing.

VIEW AND REPLY