← Return to PMR questions about prednisone, surgery limitations, pain and more

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@awilst

From my understanding of PMR, your adrenals are producing antibodies that cause pain. Prednisone helps dampen the antibody effects, but inversely makes you more susceptible to infection.
My questions are:
1. how do you determine the amount of risk with immunity dampened, when you have various invasive medical/dental procedures? ie how much risk when having surgery? how much risk in having a minor procedure, ie podiatrist working on foot? Is there a way to determine how much possible exposure to infection based on quantity (mils /per day) of Prednisone taken?
also, all this talk about Prednisone intake. My question is what is causing this inflammation? where are the tests to isolate the source of problem?
Who is identifying the source/what is triggering the adrenals to malfunction, not just treating the symptoms.

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Replies to "From my understanding of PMR, your adrenals are producing antibodies that cause pain. Prednisone helps dampen..."

@awhilst, Great questions but I don't think anyone really knows. Here's an article with some science based reference links. I think genetics may play a big part.
--- Risk Factors and Possible Causes of Polymyalgia Rheumatica:
https://www.arthritis-health.com/types/polymyalgia-rheumatica/risk-factors-and-possible-causes-polymyalgia-rheumatica

I have never heard of the "adrenals producing antibodies that cause pain". Could you post the reference you got that from so we could learn about it?