my situation is very rare. Only 300 people have it; please go to Mayo Clinic/Steve Grinstead. Also, Brain and Life April/May issue/Steve Grinstead. Google Superficial Siderosis. It has caused me to develop RLS and neuropathy among the 39 symptoms. I did have a B-12 deficiency and RLS caused by nerve damage from the SS. The RLS and the B-12 is under control as long as I take my supplements and meds. If your B-12 gets dangerously low they can give you a shot. I am not familiar with gabuenton. There is a difference between "gabupenton" and gabapentin, I think. I take my meds at bedtime. I know that I have RLS because it used to wake me up at night. Also, I did a sleep study and they said that I have RLS. I googled "gabupenton" please check spelling. Hope this helps.