I was on 4 different medications when I was first diagnosed at age 50. Unfortunately I did not have any improvement with my DEXA numbers ( which is VERY unusual). I did take a 6 year break from medication since there was nothing left to offer me. I have been to 2 Rheumatologists because my latest DEXA scan was getting worse ( it had been stable) and they both said I need to be on Evenity. During those 6 years I took a low dose Estrogen pill, walked 5-6 times a week and took vitamins and supplements( which I still do now). On this difficult journey you need to have a good MD that will help guide and support your decision.