Clinical stuldy ADT Relugolix plus Apalutamide

I am in a clinical Jansen trial at UCLA which included lupron ( old and typical ADT. Treatment ) and Erleada which is the Jansen Apalutamide. There were manageable side effects but the drugs worked good for me. Studies that I have read stated that the Apalutamide men in the trial on an average avoided the cancer progression by 24 months over the men that got the procebo. I was on the meds for 13 months with a RP mid way through. I am off of the drugs now and they are checking me every 3 months. I feel very fortunate that I got in the clinical trial and my doctors have increased my livable prognosis.

Thanks for sharing your experience. I am happy to hear that you are doing well and off of treatments.

For anyone interested, here is the link to the study:
- Multi-arm Multi-modality Therapy for Very High Risk Localized and Low Volume Metastatic Prostatic Adenocarcinoma https://clinicaltrials.gov/ct2/show/NCT03436654

Many people feel good about advancing science for future treatments. Participating in a clinical comes with perks and annoyances like additional check ins, questionnaires etc, as well as comfort and anxiety, like new treatment options or not getting the new treatment option.

@hbp and @aldenrobert, I'd be interested in hearing about your experiences participating in a clinical trial.

My UCLA doctor told me that my cancer was very aggressive and very high risk. Just days before my scheduled RP he suggested that I attempt to get into a jansen clinical trial of Erleada that he and my team of UCLA doctors were involved with. He was gentle but sincerely recommended it as even if I got the procebo he thought that I would benefit. He said that if his father was in my condition, that he would recommend the same to his father. He has a great bedside manner. In the clinical trial there were hundreds of men in a similar medical situation. My team of doctors are far smarter about these matters than I am, so I agreed to enter the clinical trial, and maybe I would be an exception to the rule and actually get a cure.
I am very very pleased with my experience and my doctors and my decision. When I needed a bone scan or a chest scan or a whole body scan or any other test, they got this taken care of right away, no waiting and to the front of the line. I have meet with my doctors every month at UCLA and each time with a new doctor on the team ( each was a professor at the med school) I was able to ask each doctor questions about my condition and my prognosis and each gave me their opinion and demonstrated that they knew my file and knew more about me than I knew about me. I hope that I am their star patient and that I will be well written up in their study. Each month I travel to UCLA hospital in Westwood CA and that is a 1.5 hour drive or more each way. The medical burdens on me are in my opinion are worth it and, of course, my family and I are hoping for more quality time and a good result. I am in favor of a clinical trial if you qualify and one is offered to you.