Hi. Do you know about the Auvelity Savings Card? Go to the website. With that, I only pay $10 a month. Insurance wanted to charge me $85. It's a great deal. Good luck!

My story is almost identical to yours. I have medication resistant major depression. I have tried both TMS and soravato. TMS helped but only for a short time. Soravato helped only if I had treatment at least once a week, which I could not afford. I started on Auvelity 6 weeks ago and, to my amazement, have felt some relief. But, alas, I have discovered that after the first 3 or 4 months my co-pay will jump from $35 a month to about $250 a month, which I cannot afford. I am on Medicare. For those with private health insurance discount cards are available but not for those on Medicare or Medicaid. I think it is unconscionable that our government does nothing to make necessary medications available to seniors on Medicare. If you can afford Auvelity you should definitely try it. The medication costs over $1000 for one month's supply, so you may want to make sure that you can still afford it if you go into insurance gap after just 3 or 4 months.

Hi there, I'm only 25 but I have a very similar experience. I did 36 TMS treatments with pretty much no improvement, tried every drug under the sun (probably 20+ meds, including the Trintellix and Wellbutrin) and 15 years of therapy. Wellbutrin gave me a tiny bit of improvement (My depression is a 9 without it, and probably a 7-8 with it) but nothing to write home about. Spravato was my next course of action until learning about Auvelity. I have been on Auvelity for a little over a week, and I have already started to see results. I haven't felt this happy, like.... ever. I've struggled with depression since I was VERY young (signs starting at age 5 or 6) and been on medication since age 10 or 11. I am also on disability and get it covered, thank goodness. It's worth trying.

So sorry. I think I get it! I have felt much the same way throughout much of my 77 years. Now I mix really bad back pain with my depression and it’s a helluva bad mix. Depression has been familial in my extended family and I now feel very badly for my children, two of whom are depressives. Nothing I have tried for either depression or pain has been helpful except I do find some relief from alprazolam, though I am very careful about keeping my dosage down. Sure feels like I am in a vice. Like you, I have a great family, good friends, a truly lovely spouse who is so kind and dear. I have shied away from all the newest antidepressants because I am so tired of things not working. I am tuned to the true beauty and wonder of Earth, but my brain is wired wrong somehow…

@bradd106 My heart goes out to you. It sounds like you've had a pretty rough time, and it's so terribly discouraging to be treatment resistant. I am 72 years old and have had MDD for the last 35+ years. I started off on zoloft which worked great until it didn't. I am grateful that it gave me a full and complete life for about 8 years, but when it quit working I, like most treatment resistant people, found it hard to go on at times. I tried everything you can think of, some of which did nothing at all, and some that made me much worse. I am happy to report that after being on Auvelity for about 10 months now that it has helped more than anything I've tried since the zoloft quit working, and with very few side effects. I'm a little late in seeing your post, but I hope you are having some success with the Auvelity. Keep us posted. Hang in there. I do truly hope Auvelity is one of those "right" things. Keeping fingers crossed for you and wishing you the very best!