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Anastrozole Brain Fog

Breast Cancer | Last Active: May 29, 2023 | Replies (72)

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@eku

A question I have is, I personally know many women in academia, research, teaching, management positions who are well beyond their menopausal age and doing a wonderful job. So, if cognitive decline is due to the lack of estrogen, how are we going to explain these brilliant women? If it is due to the estrogen blocking medication, then can we say that there's a difference between the cognitive decline due to menopause vs cognitive decline due to the estrogen blockers?

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Replies to "A question I have is, I personally know many women in academia, research, teaching, management positions..."

For me, and I believe for many women, there were many changes in my body during my menopause years. When breast cancer reared its ugly head in my mid 60’s and I was treated with surgery followed with estrogen blockers, it was like going through menopause all over again. My worst symptom is my cognitive function and loss of memory. My husband and son made fun of me to the point that I just kept my mouth shut and didn’t say anything. I have retired from work, and recently finished taking hormone blockers; however, I continue to stay by myself as much as possible. I’ve learned through this experience to enjoy my own company and the peacefulness of my alone time.

I would give this comment 10 "likes" if I could.

Some women go through menopause with nary a symptom. Some women experience it as a nightmare. So perhaps this is due in part to varying levels of estrogen lost and/or retained. If a women starts out brilliant, she could go through mild menopause and still remain brilliant. I personally was on Anastrozole and then Letrozole. When I took a 30 day break from Letrozole i noticed the difference. And I dare say I still have my aha! moments but will struggle to come up with a particular word. Brilliant women can retain their brilliance, but they may just have to work a little harder at it. AI's don't make us stupid, but they do make us work harder.