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@hopek

Colleen - Thank you for a much better title.
Jim - Yes, each of us must have our individual bag of tools that we rely on when the big D hits.
After decades of being on a combination of lexapro and Wellbutrin, with my PCP’s guidance, I very slowly weaned myself off. I didn’t know whether I still needed them or not. For a few months things were fine, then suddenly I was hit with crying spells, irritability, lack of interest in anything, etc.
My PA is recommending a low dose of lexapro but it is taking a while to kick in.
In re-investigating depression I learned about the genetic testing that may help determine which medications may work best for an individual. Maybe someone on this site has experience with this?

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Replies to "Colleen - Thank you for a much better title. Jim - Yes, each of us must..."

I've heard about it. I did the old hit and miss method of trying an antidepressant for 6 weeks, then try another, and another... until I landed on Wellbutrin, which has kept depression et al at a manageable level for 17 years. Because depression is still an issue, I can't imagine going without medication, though I understand that I may need to make a change at some point. 5 or 6 years ago my psychiatrist added Mirtazapine when I was having a rough time. I'm still seeing a therapist, though only every other week now. Thoughts of wanting to end my life are always lurking around the fringes of my consciousness. I wish they were gone completely and that could happen some day. But for now, I have to be mindful of my family and avoid ruminating on suicide. To the vast majority of people that's a totally foreign concept, and they have the quick solutions and cliches that make sense to them, but are meaningless to the at risk person.

But I've said more than enough for today. I hope you get your meds in place soon.

Jim