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Chronic constipation alternatives

Digestive Health | Last Active: Apr 30, 2023 | Replies (65)

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@jcarndt

"My problem became significantly worse after beginning Prolia injections for osteoporosis. Sorry not a big help, but try the senokot occasionally and see."

Are you still taking the Prolia injections ? I've been getting them for at least five years or more for steroid related osteoporosis. Now I'm beginning to wonder if the Prolia has screwed me up. I have chronic, every day is a battle, constipation.
I've had Crohn's disease for many years, and like most people, loose bm's were my main problem. Then at some point it started morphing into constipation and here I am. I missed my last shot that was due in late December and am now wondering if I should just stay off......

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Replies to ""My problem became significantly worse after beginning Prolia injections for osteoporosis. Sorry not a big help,..."

Be careful. Just stopping Prolia is risky behaviour! Puts you at risk for spontaneous compression fractures that can happen for up to 2 years after stopping without "relaying" on to another drug (one of the bisphosphonates). The longest you should go between injections is 7 mos.
Yes, I am still on Prolia. Now I am taking break from Senokot and on Miralax. Less cramping but tons of bloating.
I firmly believe it is the Prolia that has made my g.i. issues much much worse (both constipation and acid reflux). Now to get off I would have to do intravenous delivered Reclast and then be able to take break from drugs for a while. The Reclast can stay in system for 18 mos. Who knows what that drug will do?
Also I need a lot of invasive dental work and I think working on patients on bisphosphonates worries dentists even more than Prolia.
Please speak to your doctor re stopping Prolia. At the osteoporosis clinic I go go the endocrinologists would strongly advise against this as does Amgen the drug company that makes Prolia.
Are your g.i. issues better since you stopped?