Very encouraged to read about such solid results from a year of Evenity, and that everyone is living through it, in any case! Like many who've posted here, I was very nervous about starting this drug and dove into the medical literature to get a real sense of the risk. Unfortunately, the research to date has not established a biological mechanism to explain a link between the drug and any elevated risk of heart attack or stroke. My endocrinologist acknowledged this and the fact the longitudinal data about potential risks and long-term effects of this drug just don't exist yet. Still, he said it's the best option for me to build bone density. (I was on Prolia for five years, had a modest gain after two and nada after that; Fosamax is out because of GI problems; and Tymlos hasn't come up, although the cancer risk, if slight, turned me off.) But he did order a cardiac calcium scan and additional blood work to assess my baseline risk before my first injections in January - the good results of those gave me the confidence to start Evenity. Something for those still on the fence to consider requesting...