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PMR and Methotrexate

Polymyalgia Rheumatica (PMR) | Last Active: 1 day ago | Replies (200)

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@christinetoo

Hi all,
New to post. Had PMR in my 50’s and did well on conventional treatment. Had been off prednisone for 6 years with no pain issues… I guess I was a lucky one. But fast forward to now: after the year on prednisone I developed mild glaucoma, hypertension, and osteopenia (all which could have occurred without the pred, but probably accelerated with it). So, now I’m in my 60’s and PMR is back and prednisone is off the table. I will be starting methotrexate in a few weeks (after falling and fracturing my wrist, can’t start anything until healed). I heard it takes a few months to feel pain relief. I’m nervous but don’t really have any other option. Hope to hear from some who have had success with methotrexate only for pain management ( my goal is to move the needle from 8/10 in the morning to 4/10… ).

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Replies to "Hi all, New to post. Had PMR in my 50’s and did well on conventional treatment...."

Welcome @christinetoo, Sorry to hear of the prednisone is off the table. I had 6 years between by first and second occurrence of PMR also but used prednisone for both. I will be 80 in a few months and have osteopenia and hypertension also. I made some lifestyle changes the second time around that helped me including exercising more and eating healthier. I eliminated fast foods, most processed foods and tried to eliminate sugar but I still have a ways to go with that.

You might also find these two discussions helpful:
-- Alternative to Prednisone for Treating PMR?: https://connect.mayoclinic.org/discussion/alternative-to-prednisone/
-- PMR: Are there treatment alternatives to Prednisone?: https://connect.mayoclinic.org/discussion/alternatives-to-prednisone/.

It sounds like you might already be keeping a daily log for pain levels. Have you made any lifestyle changes to help manage the pain?