I have switched from Anastrazole to Letrozole and now Tamoxifen due to side effects. My onco wants me to go back to an AI as it is preferred for postmenopausal lobular BC plus take a bone med . The Tamoxifen does not require a bone med as it helps build bone, which is a plus, but it is also has blood clots and uterine cancer as side effects and is not the best med for lobular BC as it has a higher recurrence risk. If I go back to an AI, I will need to take something to prevent further bone loss. I'll have to research all of my options of bone meds before deciding as I know there are injections, infusions, pills, etc. All so difficult as last thing I'd want to do is add another set of symptoms to my growing list. I'm wondering if there is one place to look for comparisons of all the different options. I've also heard once you start the drugs you are supposed to continue, which sounds absurd, but once you stop the bone may be in worse shape than previously....not very easy decisions to be made.