Thank you so much for your reply...I appreciate it so much. So, I have only been on this taper plan 6 days. I started this with: an addition of Prozac 10mg a day and Effoxor went down from 300 (300 a day since 2010, before that 250 since 2001) from 300 to 262.5. Each Bump down is every 8 to 10 days but the nurse practitioner states it's up to me to decide how long to stay on each plateau. So I only have one week of experience. You probably should write me and ask me after 3 months. I have experienced various things since reducing this past week but it has been tolerable. Any brains outside have been mild but I've been having bad dreams, problems sleeping, restless legs, malaise...and it's hard to know how much is the Effexor and the the addition of the Prozac And the symptoms of discontinuation. I also am ADHD and take Effexor and this medication is probably not gonna be able to be located within a 100 miles of where I live soon and that will be an additional factor. It has been often unavailable in my area for several months. This problem does not have to do with supply chain --it has to do with the increase of people that were assessed and diagnosed during the pandemic. Hope That helps. I've taken prozac before and it does have some side effects but for me they not too bad unless I decide to become sexually active.