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About N-Acetyl L-Cysteine (NAC) and finding it

MAC & Bronchiectasis | Last Active: May 17, 2023 | Replies (53)

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@roz14

Hello Irene, Thank you for answering me. I have learned a lot from reading what people say and how they have dealt these diseases. To answer your question, my local pulmonologist gave me the prescription but I did the research and asked for it. I went to NJH because I wanted better care even if it was in a different state and I have definitely gotten it. The doctors at NJH just were not convinced that NAC was really helpful. I don't know about glutathione but I will look it up. Have you found it to be helpful and if so how? I have not been treated with other antibiotics. How does Mucinex work for you? It would be great if I learned about another tool to clear my lungs a little bit more. Right now I cough a lot but several months ago I felt much better without this cough.

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Replies to "Hello Irene, Thank you for answering me. I have learned a lot from reading what people..."

Hello again Roz. Glutathione and NAC are interrelated. Glutathione is considered the "mother of all antioxidants" and NAC is a precursor of L-cysteine that results in glutathione elevation biosynthesis. So I am not sure why one would want to use NAC and not Glutathione. If you google Nebulizing Glutathione you can read up on it. I think it is supposed to be good for general lung health but i also think it helps loosen mucus to some extent. I cannot know for sure if it is helping me but I hope so and I keep using it every other day. It has a sulphur taste at first but then that goes away quickly and it is tolerable. I mix it with my 7% saline in a certain way. I read a study that compared several things for mucus. NAC and guaifenesin were two of the things. Mucinex original formula is just Guaifenesin time released. Of the three things Mucinex was found to be the most effective. I find it helps but everything produces side effects for my body so i do not take it daily. For me it had the best results with the least side effects to expel mucus. Of course 7% saline is the most important for that twice a day followed by Aerobika. I learned that using the Aerobika lying on my back and sides as well as while sitting has helped a great deal to get the stubborn mucus out. Sounds like you use the Toby every day or every two weeks? I hope that keeps helping as it can build up resistance. My Pseudomonas is chronic form and i would really like to find an antibiotic i could tolerate and take now and then. My understanding is that there are only two oral ones and a couple of inhaled options including the Toby. All the rest are IV and require hospitalization initially at least.

rox14 & @irenea8 - I choose to use NAC in the oral supplement form instead of inhaled glutathione because I have hyperreactive airways, and avoid inhaling anything that I can get in another form.
In addition, NAC has anti-inflammatory properties, which when taken with my other medications helps my arthritis pain.

Our bodies all behave differently, and finding the right combinations is always a challenge.
Sue