I believe the current thinking is chemo first to shrink/kill as much as possible. Then targeted radiation perhaps. For me, folfurinox shrink everything and result was much necrosis. Y90 to my liver stabilized the shrunken liver tumors (that merged together) so that I could have a pancreadectomy in December. Ca 19-9 scores are rising (179) so will find out results of PET and ultrasound tomorrow. If no new metastases, next step will be liver surgery

All the while I feel great and am working full time. I have lost about 30 lbs throughout 2022 and certainly had slump days but nurses were the best resource and helped me discover new ways to bounce back each time. Enjoy each day, make it productive, and never give up hope!