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Myopathy?

Polymyalgia Rheumatica (PMR) | Last Active: Feb 9, 2023 | Replies (16)

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@dadcue

This is something I found to be interesting. How was your psoriatic arthritis treated?
https://pubmed.ncbi.nlm.nih.gov/24037820/
My rheumatologist has always told me that having one autoimmune disorder puts me at risk of having other autoimmune disorders.

I was diagnosed with reactive arthritis with uveitis at the age of 32. These two disorders are part of the spondylitis family of autoimmune disorders. Psoriatic arthritis is part of the same family.
https://www.myspondylitisteam.com/resources/spondylitis-types
I took prednisone frequently for flares. My ophthalmologist would prescribe mega doses of prednisone to quickly get flares of uveitis under control.

When I turned 52, my rheumatologist added PMR to the mix of autoimmune disorders I already had. I now have chronically elevated CK levels which suggests a myopathy is also happening. My rheumatologist doesn't know why my CK is elevated. Myopathy can be autoimmune related or myopathy can be caused by a medication such as a statin or prednisone. My CK level stayed elevated when both medications were stopped so not likely a medication I take.

I continue to have muscle wasting which could be PMR related.
https://pubmed.ncbi.nlm.nih.gov/26915593/
At this stage my rheumatologist just says that I have a full range of rheumatology problems. Now I just seem to get "idiopathic" problems which is a fancy term for "I don't know why!"
https://medlineplus.gov/genetics/condition/idiopathic-inflammatory-myopathy/#:~:text=Idiopathic%20inflammatory%20myopathy%20is%20a,can%20occur%20at%20any%20age.

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Replies to "This is something I found to be interesting. How was your psoriatic arthritis treated? https://pubmed.ncbi.nlm.nih.gov/24037820/ My..."

Thanks for all the information dadcue. It sounds like you’ve been through so much starting at such a young age! Come to think of it, the Bell’s palsy and facial weakness when I was 31 and 32. Thats when the weird stuff sort of started. I digress. I will look into the links you provided. She wanted me on some medicine that messes with your immune system. (I can’t remember its name.) That probably covers most of them. I think it was a dmard. She wanted me to start it to prevent its spread to other joints. She tried me on low dose steroid to see if this med would help. It did help. But I’m not confident about trying such a serious med. We thought seriously about it but decided against it. I didn’t have active disease at that time, so I thought it might be too aggressive a treatment. I have enough issues without opening myself up to other things. I thought if it “activated” then I would reconsider depending on what’s happening.
Thank you for all the information.

Do you know if general anesthesia could bring on myopathy? It happened a day later.

Myasthenia was on that list. This was looked into some years ago. Hmmm. Ill bring the myopathy to both rheumy and neuromuscular dr.

I am sorry for all you endure. Myopathy. Its a nasty and painful thing. To have prolonged myopathy I could not imagine. I suppose my reuhmy will check my ck levels. See if it registers. Prednisone. It eases the pains but sends the pulse rate up there and that is sustained elevations (about 115-124) for a day or two. Made my blood sugar numbers go up. My pulmonologist said this is a medication we cant use because of that.

I mentioned the thyroid issue I’m now having (the nodules and cyst). In the past when I was in my early 30’s and I had suppressed TSH with normal t3 and t4. palpitations, temperature would come and go, thin. The doctor thought it was a mild case of intermittent graves. I was not on a blood pressure med back then. He put me on a medication for 6 months, I think it was Tapazole. I think that might be an autoimmune condition. Since then, I gained, and. The situation seemed to resolve. I’m going to ask the endocrinologist about the thyroid and give her my history, however brief that was. Way back then i was told I had sjogrens. My Ana has been positive 5 times that I know of. Low tigers, speckled pattern 3x reflexive test was negative. Low IgM. With a strange history, not exactly sure if this ties into anything present. We she see. I think time will tell. Thank you for your help!!!!