I have been taking anastrozole for 6 months following a Grade One ductal carcinoma removal via lumpectomy last May. They said they got all of the cancer cells. I did not have radiation or chemo, but I really dislike the side effects of anastrozole and am considering going off it. I have an appt. next month with the onco. I will also ask about substitutions. I have a heightened level of anxiety, digestive disturbances and weight gain in spite of a moderate diet and walking. I took a three week vacation from the med [with the approval of my onco] before xmas because I was so stressed. I did not feel normal until two weeks later. I feel caught between a rock and a hard place re: continuing to take it or giving it up. According to my doc, I have a 6-7% chance of a recurrence without completing the course of med, and a 3% chance if I finish the whole 5 yr. course. Has anyone else faced this kind of decision. I am 74 and I dislike the thought of enduring these side effects for 4.5 more years. Would welcome any thoughts on the matter.