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← Return to Letrozole: When will I start feeling/seeing side effects?
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Letrozole: When will I start feeling/seeing side effects?
Breast Cancer | Last Active: Apr 17 5:23pm | Replies (127)Comment receiving replies
Thank you for your info on manufacturers. Please tell us the info source where you learned Letrozole eliminates lingering breast cancer cells. I thought it was limited to disrupting estrogen.
Replies to "Thank you for your info on manufacturers. Please tell us the info source where you learned..."
Aromatase inhibitors lower estrogen levels by stopping an enzyme in fat tissue (called aromatase) from changing other hormones into estrogen. Estrogen can fuel the growth of breast cancer cells. [Cancer. org]
My BC is HR+, HER2- and I'm postmenopausal. So I look at Letrozole as 'playing clean up' role in my treatment regimen.
AIs, like Lestrozole, are used to shrink tumors sometimes in more advanced cases before surgery. When the tumors do not have the Lestrozole to "feed on" they shrink.
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@pbnew these meds decrease estrogen below detectable levels. The estrogen fed our cancers, so disrupting it starves the cancer cells. I believe that is the idea. Your doc can explain!