I have vasculitis and not sure if Wegeners has been positivly identified in me. But I am firm on the stand I take that no prednisone will I take. I had PMR and took prednisone for 13months and it did such damage and I put on so much weight I didn't recognize myself in the mirror. I've been off of it for 5yrs now and have gotten to a normal weight. My bones have suffered and I have high blood pressure but it is still better. Now if the medication I am on isnt helping that's it! I wont take prednisone anymore. I'm posting this so others know the dark side of this medication. I'm on Nucala at the moment 3 mo in and hope it will make a difference. I hope the best for all who see these posts. For me its helpful to know I am not alone in this journey.