Hi there, my understanding is bile breaks down fat. The pancreas creates bile and sends to the gallbladder to store. The gallbladder releases when you consume fat. When the gallbladder is removed the pancreas still creates bile but has no where to store and drips it into the intestines slowly. I was suffering every time I ate anything high in fat. A hamburger, steak, loaded baked potato are examples. I would be up all night. Now that I take enzymes, I can pretty much eat anything. As a footnote, I had my gallbladder removed when I was 30 and now 60. Never had a problem until I hit 50. Hope that helps and is clear. I am frustrated with conventional doctors as they all knew I had my gallbladder removed and ordered endoscopy’s but never once discussed enzymes or probiotics with me.