I agree with Jondoetx, the MRI guided biopsy is the latest and best biopsy procedure available. After I had lesions show up on my MRI, I was in the same camp as you - Wanted to move as fast as possible. However, 2-3 weeks is pretty quick to go from MRI results to biopsy. Please note, if your biopsy comes back positive and you decide to move forward with a radical prostatectomy, your prostate will need at least six weeks to heal prior to surgery. To give you context of my situation, my doctor (not Mayo, small hospital in Iowa) did not inform me of my increasing PSA levels (high velocity) for over six years - The only way I found out about my high PSA was through a doctor friend that reviewed my medical records at an unrelated appointment. Thus, based on my experience, weeks will most likely not cause any problems, it is years of ignoring the data that will. You are on the right track, keep a positive attitude and address any cancer proactively if it is found in the biopsy.