I had a lumpectomy 6 months ago then one week only of radiation (new protocol, 3000 Gy in 5 sessions). I am on 20 mg of tamoxifen, not AI, because I have osteoporosis. My hips are at -2.9 already. Tamoxifen is supposed to have an overall preserving effect on bone (may be small loss at first, but stabilizes after that). At my upcoming appointment I am going to ask about the possibility of dropping down to 10 mg or 5 mg of tamoxifen. Latest research is showing it has good results with the lower dose. My side effects so far are: warm flashes first 2 weeks only, brittle finger, toenails and hair (maybe stress related, though). My memory has gotten worse. Questionable eye issue, increase in clear floater or cataract in one eye, am seeing ophthalmologist this week. I’m 68, had ER and PgR positive DCIS, no nodes, HER2 unknown.