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Tamoxifen and mental health

Breast Cancer | Last Active: Jul 1 11:46am | Replies (71)
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@auksst

Arimidex works differently than Tamoxifen. Arimidex blocks the production of estrogen so your body is not getting estrogen and thus all the concerns associated with lack of estrogen in your body. Tamoxifen blocks the effect of estrogen on cancer cells. Your heart and bones are still receiving the benefits of estrogen.

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Replies to "Arimidex works differently than Tamoxifen. Arimidex blocks the production of estrogen so your body is not..."
exk | @exk | Feb 8 9:14am

Great explanation and brings me to the question I can’t seem to find the answer to. I requested a break from Anastrazole 10 days ago and oncologist ok’d. Was on it since June 2022 and more than 12 months in, developed joint/muscle pain and daily palpitations which just wear me out (checked by cardiologist and all is good). To early to be sure that my issues will improve. But after stopping Anast., I assume estrogen reappears and I am wondering if there are any side effects associated with the sudden release of new estrogen?

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