Abemaciclib (Verzenio) and fulvestrant (Falsodex) Treatment

Posted by thielmann1 @thielmann1, Jul 1, 2021

I started on a treatment of Abemaciclib and Falsodex for recurrent breast cancer 2 weeks ago. So far, I have not had any side effects. I have heard that a typical side effect is diarrhea. Does is take a few weeks before that starts? Is anyone taking these drugs and have you had side effects? Do you think it has been effective for you?
N

Interested in more discussions like this? Go to the Breast Cancer Support Group.

nikki727 | @nikki727 | May 30, 2022

In reply to @nikki727 "I’m currently on abemeciclib and letrozole. I have been for 3 years. I have not ever..." + (show)

I occasionally have some 💩💩💩 but I also think that happens when I eat crappy. My hands peel very bad and get raw sometimes but that has slowed down a lot over the past year. I’m not sure why but it makes me happy.

eku | @eku | May 30, 2022

In reply to @jbp "I just started this treatment 2 months ago and see that you started in July. Just..." + (show)

I have been on Verzenio + anastrozole since February (MBC). I've had diarrhea during the first month but it's mostly gone now. Still going on are hot flashes and some fatigue. It's pretty recent for me so I cannot say much to its effectiveness. I, too, am having a difficult time with the diagnosis itself.

jbp | @jbp | May 30, 2022

In reply to @nikki727 "I’m currently on abemeciclib and letrozole. I have been for 3 years. I have not ever..." + (show)

I'm not familiar with letrozole....is your cancer a recurrence?

jbp | @jbp | May 30, 2022

Just wondering is your cancer a recurrence? Have you had any scans since you started treatment? I live 7 hours from Mayos and am headed there tomorrow for 2 days of scans, bloodwork, and my fulvestrant injection. I'm anxious to see what the test/scan results show.

cctoo. Catherine Crowley | @cctoo | Jan 11, 2023

In reply to @jbp "Just wondering is your cancer a recurrence? Have you had any scans since you started treatment?..." + (show)

will be getting Fulvestrant injection s after radiation . How is that? Side effects? I am most concerned about left chest radiation .how to prevent heart issues.

Colleen Young, Connect Director | @colleenyoung | Jan 22, 2023

In reply to @cctoo "will be getting Fulvestrant injection s after radiation . How is that? Side effects? I am..." + (show)

@cctoo, heart issues can be a concern with some treatment options. You may ask about a cardio-oncology specialist or department.

Mayo Clinic offers a program to address heart problems associated with cancer treatment called cardio-oncology or for people who have a pre-existing heart condition when diagnosed with cancer. The Cardio-Oncology Clinic (https://www.mayoclinic.org/departments-centers/cardio-oncology-clinic/overview/ovc-20442193) evaluates people prior to cancer treatment and patients who have experienced side effects due their treatment, and can help evaluate treatment when you have both cancer and heart conditions.

Do you have access to a similar cardio-oncology program?