C reactive protein, sedimentation rate and LDH testing
Did you test for the three tests to see if you have cancer? C reactive protein, sedimentation rate and LDH --- if all three are high that is not great.
Interested in more discussions like this? Go to the Breast Cancer Support Group.
LDH measues lactic acid.
CRP has been connected to heart risks, by my docs.
Sedimentation rate has been connected to autoimmune diseases by my docs.
@polianad22 can you provide a link to show the connection of these three tests to cancer?
Elevated plasmatic lactate dehydrogenase (LDH) levels are associated with worse prognosis in various malignancies, including metastatic breast cancer (MBC). Nevertheless, no data are available on the prognostic role of LDH as a dynamic biomarker during first-line treatment in unselected MBC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497911/
Thank you! Very interesting about the LDH. (But I don't see anything about CRP and sed rate....)
Higher CRP-levels are indicating a worse prognosis in early breast cancer after NACT in this retrospective analysis. These results justify further investigation of CRP as a biomarker of long-term prognosis in early breast cancer in prospective trials...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377048/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740825/
Thank you!
One problem with C-reactive protein test is that they don't identify the source of inflamnation. My former cardiologist (who's such a great doctor that I wish he specialized in everything and was a veterinarian as well so he could address any woe likely to befall any family member, but I digress) explained some of the shortcomings of the test when I had a high number and was alarmed. At the time I had just lost weight and he pointed out that dieting alone frequently results in an elevated C-reactive protein result. Post-dieting CRP results a month later showed normal levels.
Interesting! My doctor was testing my CMP and some reason lab did CRP instead and came back 11.10! She was shocked but wanted to wait 3 months to retest. I’m not good at waiting so had a different lab recheck and it was 3.1. Still high but much better. I had a UTI awhile ago maybe that’s why it was so high?