@divinewisdom28 You are so very welcome. I'll see how it goes over the next week or two and give you an update. I am definitely treatment resistant so I'm really hoping this works. The only thing my doctor has recommended that I haven't tried is Spravato nasal spray. I'm not really adverse to trying it. It's more a matter of logistics. My doctor has had a lot of success with Spravato but he is in Dallas and I live about 200 miles south of there. I found a doctor close to me who is willing to administer it but they will not allow you to drive yourself to or from appointments because of possible side effects. They also monitor you for a couple of hours after using the spray. I don't know anyone in this area I could ask to take me to appointments. If the Auvelity doesn't work I may see if they will let me take Uber to appointments, although they've said they are not thrilled about that option but would probably allow it. I'm getting ahead of myself since I don't know yet if the Auvelity will work but I'll be reporting in! God bless all of you that are suffering with depression. I find that it is so hard for my friends and family to understand. I'm grateful for this website!