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Concerned about the side effects of anastrozole

Breast Cancer | Last Active: 1 day ago | Replies (1928)
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@gldilli

I have been taking Anastrozole for 10 months. My biggest concern is progression of my osteopenia to osteoporosis and elevation of my cholesterol levels. Like others have mentioned my aches have been kept in check by lots of walking and strength training. I even took off the extra 20 lbs that I was carrying when diagnosed. If the cholesterol keeps creeping up despite diet and exercise then I need to consider if a risk for cardiac event or stroke outweighs the risk for BC recurrence.

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Replies to "I have been taking Anastrozole for 10 months. My biggest concern is progression of my osteopenia..."
magmcdonah2 | @magmcdonah2 | Jan 16, 2023

Congratulations on weight loss, it’s a struggle to balance benefits with side effects.

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anjalima | @anjalima | Jan 16, 2023

I’m in the same situation, 10 months in, lost 15 since diagnosis last January, minimal side effects but concerns for the unseen. I’m focused on mitigation; reduced cholesterol foods, increased weight bearing exercises, upcoming appointment with an endocrinologist and repeating a DEXA at one year ( vs. two) to monitor any possible trends. In the meantime, when I take that pill, I envision the reduction of any estrogen that could potentially harm me.

This is definitely an ongoing journey.

Blessings on the path 🌸

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mpirruccel | @mpirruccel | Jan 16, 2023

I have been on anastroloze for 2 months now and have noticed increasing pain in one knee as my other knee is a replacement and it always hurts a lot. I had dexa scan showing worsening osteopenia before starting anti estrogen pills so am taking Fosamax which unfortunately also causes joint pain. Will take for 2 years. My tumor was small, 3 mm, clean lymph nodes so I chose to not do radiation as it has significant side effects which could be long term. So am depending on this little pill to help keep a recurrence from happening.

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amajok | @amajok | Jan 17, 2023

I am in the same situation with rising LDL and I am thinking of switching to Exemestane. it should not affect blood lipids at all. Do any of you ladies have experience with AI change in order to get blod lipids lowered?

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