There is no underlying cause with my MP either, at least I hope not since they are more reluctant to follow any guidelines at my medical facility. Please excuse my non reply's to others if you did send me information regarding MP or wanted discussion. I was being bombarded with all auto immune disorders and it became a bad distraction when your phone and watch would light up a dozen times a day with non MP issues. All I can say is that I have a pretty good footing about what MP is. It is the problem with NE medical facilities that lack the caring for refined diagnosis and treatment. I can say without a doubt from Brighams Womans and Dana Farber that laxatives isn't the prime treatment for relief as this was what my so called specialist best guess solution.