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Anyone here with Hurthle Cell (Oncocytic) Carcinoma?

Thyroid Cancer | Last Active: Jan 19 8:13am | Replies (62)

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@paul300

Colleen,
--->"Hurthle cell carcinoma, which is a variant of follicular thyroid cancer, tends to spread first to the regional lymph nodes."

Can you double-check this? Everything I have read seems to say that HTC does not tend to spread to regional lymph nodes initially.

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Replies to "Colleen, --->"Hurthle cell carcinoma, which is a variant of follicular thyroid cancer, tends to spread first..."

@paul300, thanks for jumping in to question the accuracy of HTC spread. I did some more digging and found conflicting information.

"Hurthle cell thyroid cancer is now defined as a follicular thyroid cell “derived” cancer and not a variant of follicular cancer itself."
- Hurthle Cell Thyroid Carcinoma https://www.ncbi.nlm.nih.gov/books/NBK568736/

"Hurthle cell cancer can spread into the lymph nodes of the neck. In fact, at least 20% of hurthle cell cancers will have spread to neck lymph nodes on their initial presentation." https://www.thyroidcancer.com/thyroid-cancer/hurthle#:~:text=Hurthle%20cell%20cancer%20certainly%20can,nodes%20on%20their%20initial%20presentation.

"About 20–30% of HCC cases have metastatic extension at the time of initial treatment. The most frequent sites of metastasis are the lungs and bones." https://academic.oup.com/qjmed/article/112/6/453/5255882

"Hürthle cell carcinoma (HCC) is a rare tumor that tends to metastasize to the lymph nodes." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931345/

You won't be able to share links yet because you're a new member. But maybe you can tell me where to look for further information about typical spread for HCC. It is confusing. Do you have metastatic HCC?