I had rectal cancer eight years ago. Before I had the surgery.One oncologist gave me the Xeloda And radiation.To shrink the tumor.That put me in the hospital for two weeks very severe diarrhea. Couldn’t eat it was horrible. After that I went to Moffitt cancer center which is in Tampa Florida. It was the best decision. I could not tolerate Xeloda Or maybe it was the radiation but I didn’t do that again. I had to wait six weeks to heal before I had surgery I’m sure there are people who can tolerate that drug but my new oncologist wouldn’t give me that to do and I had a successful surgery. I can’t say there are no problems but I’ve dealt with all of them with a good attitude very important