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Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?

Prostate Cancer | Last Active: Sep 14 7:33am | Replies (188)
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@happster

Can someone tell me the protocol for the Pluvicto treatment? That is, if a PSMA scan is positive and treatment is recommended when would treatment start (ie next day, next week, 6 weeks?) and how many days would we expect to be at Mayo? One day for the treatment, but are there tests before or after? Travel limitations? Thank you!

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Replies to "Can someone tell me the protocol for the Pluvicto treatment? That is, if a PSMA scan..."
Colleen Young, Connect Director | @colleenyoung | Jan 22, 2023

Hi @happster, according to the dosage guidelines, PLUVICTO dosing schedule is administered every 6 weeks for up to 6 treatments

PLUVICTO solution for injection contains 7.4 GBq (200 mCi) (at time of use)
- Administered once every 6 weeks for up to 6 treatments, or until disease progression, or unacceptable toxicity
- Slow intravenous (IV) injection (1 to 10 minutes) or infusion

You can read more here: https://www.hcp.novartis.com/products/pluvicto/psma-positive-mcrpc/dosing-and-administration/

@bamaples @leebeth @suwairi @patgwenn @ncoic @bburgess1 @john99 @royalbee can share their first-hand experiences about dosing, travel restrictions if any, related testing and what to expect.

Happster, has Pluvicto been recommended for you?

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