← Return to Xeloda for colon cancer - Scared about side effects and need support

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@martin77

Thanks for your Christmas greetings. I hope you had a good day and that your first day of Xeloda has gone well. Have you experienced tingly fingers yet? That's an easy side effect to live with but I sometimes wear thin gloves when handling cold objects. I'm finding it's a bit like riding a roller coaster - some days are great and others difficult and I've yet to discover the reason for the variances. I seem to be tolerating Xeloda quite well and so I suspect it's about finding the right diet to ensure a comfortable bowel at all times.
My treatment started with an infusion of Oxaliplatin last Thursday which lasted around 2 hours. That was easy. Since then I have been taking 3 x 500mg pills of Capecitabine (Xeloda) twice a day but the first 3 days also included steroid and anti-sickness pills which, combined, might have been the cause of the awful constipation a week ago. I've stopped taking laxatives and so it now seems to be a question of diet management. This roller coaster experience has resulted in some days, such as yesterday, when I have felt very well (5,500 steps achieved fairly easily), but not quite as good today (only 3,300 so far). Maybe it was the first red wine for weeks when a couple of grandkids visited yesterday! I hope your experience goes well and that you have no discomfort.
We have had lovely sunny weather over Christmas with temperatures of 9C / 48F at times. Good to hear you're not affected by the icy conditions elsewhere. Keep in touch.

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Replies to "Thanks for your Christmas greetings. I hope you had a good day and that your first..."

Hello, I have been thinking about you and wanted to wait until I had a few doses before explaining how I am feeling since I started yesterday 12/26/22 with the Xeloda. I am sorry you have been on a roller coaster and hope that your symptoms will subside and that your experience for the rest of the journey will be a positive one. It has not been quite a week for you, so it may just take a little longer for your system to settle in. I too am taking 3 of the 500mg tablets 2/day, and so far have not had any side effects. While I am tolerating it well so far, it has only been 3 doses as of this writing. I will take my 4th dose tonight and then continue tomorrow through this week and next before having a week off. I am not getting too excited at this point because it has only been two days, and not sure if things will change once I get further into the routine and the medicine has really kicked in. I will post another update by this coming weekend once I see how things go. I meet with my oncologist on January 6th for my first follow up since I last saw her after my surgery and before taking the treatment. Not sure if my routine will help, but what I do is take the Ondansetron (anti nausea medicine) under the tongue so it will dissolve while I have an empty stomach. I do this about 30 minutes prior to eating breakfast (same with dinner). Then I have my meal prepared to eat at least half of it after that 30 minutes are up, and start taking one pill at a time, slowly, with water, and then taking another bite of food. I drink hot ginger tea with my breakfast, and keep ginger chews (from the health food store) on my kitchen counter in case I need them, along with ginger ale, and even ginger snaps (haven't needed any of that yet, but it's there just in case). After the first pill, I take the second one a few minutes later, again with some food and water and sips of ginger tea. The same with the third tablet. I do this process slowly so that the 3 tablets are taken in about 8-10 minutes. I repeat this at dinner time. So far so good, but as I mentioned, I am just starting, so not sure if I will continue experiencing the same outcome over the course of the next few months. Once I finish in 6 months, I will get another CT scan, so of course there is always going to be anxiety when we are re-tested in the hopes that all goes well and nothing else shows up. Do you still have to take steroids and infusions, or was that just for the beginning? Please keep me posted on your progress, and I too will do the same by the end of the week or during the weekend. Meanwhile, I wish you the very best and pray that we both get through this ordeal as best as possible without any mishaps. Happy New Year to you and your family, and continue to stay safe and warm. Sending you positive thoughts my friend. We will get through this!

Hello again, I am about to start my morning ritual on day 3. I did have a little constipation this morning upon wakening, and realized that I also need to do something about eating more well balanced foods to include more vegetables and fruit--especially grapes. I have gotten into a bad habit prior to the holidays with eating foods that I normally don't. Not only have I gained weight, but am also eating foods that are not good for the treatment and with just having the colon surgery. Starting today, I am going to eat more of the good things and go back to eating the fun stuff in moderation. I have heard that prune juice is also good to have around in case one has this problem. Definitely need to keep a gentle laxative on hand. I will let you know how it goes, and I do hope that you will have better success. Is next week your one week off? All the Best in the New Year!