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Mesenteric Panniculitis or Sclerosing Mesenteritis

Digestive Health | Last Active: Dec 18, 2024 | Replies (1519)

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@eddieg

I have been going thru the MP type issues, had pain in upper left quadrant (dull deep pain) and feeling sick, bowel issues not feeling well. Had a CT scan done, GI doctor called me same day and said report showed inflamation/infiltration at Root of mesentery, misty sign and lymph node enlargement in area. I was referred to oncologist. I read the CT report and said a diagnosis of MP and differential diagnosis of early lymphoma. After the million dollar work up that included a PET scan because they were sure I had lymphoma it came back not showing anything, along with negative tumor blood work, though my C-Reactive protein was very high. I had upper GI scope, colonoscopy that nothing came up serious, diverticulosis and some polyps removed. I have a follow up CT scan in a month and guess I will have to live with this abdominal pain because they have no clue about this MP the radiologist seen . Frustrated and want to get treatment.

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Replies to "I have been going thru the MP type issues, had pain in upper left quadrant (dull..."

This is pretty much exactly my symptoms, diagnosis, and experience. After CT and PET scans and colonoscopy and bloodwork to rule out lymphoma, my GI diagnosed Sclerosing Mesenteritis. She is recommending 40mg Prednisone for 6 months with 10mg Tamoxifen plus sulpha antibiotic, then 6-month taper. That seems like a long time to take such a high dose of prednisone, and I notice others on this thread started to taper after just a few weeks or a month. I am very curious what treatment you got, and what the results were?