← Return to Tapering off of Prednisone

Discussion

Tapering off of Prednisone

Polymyalgia Rheumatica (PMR) | Last Active: Feb 28 5:49am | Replies (313)

Comment receiving replies
@gingerraspiller

Can anyone comment about what a biologic is and if you have used it to fight PMR? What are the pros and cons of biologics? Please share any links.
Thanks
Ginger

Jump to this post


Replies to "Can anyone comment about what a biologic is and if you have used it to fight..."

There is another discussion that you might find helpful
-- Actemra (Tocilizumab) to treat PMR??:
https://connect.mayoclinic.org/discussion/actemra-tocilizumab-to-treat-pmr/
Here's a reference that also might be helpful:
-- Biologics may help reduce the need for steroids in PMR:
https://blogs.bmj.com/rheumsummaries/2022/04/16/biologics-may-help-reduce-the-need-for-steroids-in-pmr/

The following link explains what a biologic is.
https://www.verywellhealth.com/biologics-or-biological-agents-2615117?utm_campaign=15823081431-9b73ed45334a76&utm_source=googleawpaid&utm
Biologics are being used more and more for rheumatic disorders that don't respond to conventional treatments. Biologics aren't usually the first treatment that is tried. The cost of treatment is the biggest drawback because biologics are expensive. Biologics also can have side effects that are potentially harmful just like other medications.

So far, there isn't any biologic treatment that is FDA approved for PMR. My rheumatologist needed to submit a request to get Actemra approved for me. The reason it was approved was that I took prednisone for almost 13 years and I was unable to taper off no matter what was tried. I tried other alternatives like methotrexate and leflunomide without any improvement. Actemra was more like the last resort for me. My rheumatologist didn't want me to take prednisone for the rest of my life.

My rheumatologist didn't know whether or not Actemra would work for me. We are all different so there is no guarantee it will work for everyone.

I was just lucky that Actemra has worked well for me and I haven't had any serious side effects. Actemra allowed me to taper off prednisone. I still take Actemra to treat PMR and some other autoimmune disorders.