I was diagnosed in April 2022 with TNBC. I did twelve weeks of Carbo / Pacitaxel /Immuno on the ISPY 2 study then switched to AC x 4 every three weeks with Pembro. Then surgery. They want to see how the meds affect the tumor before removing it. This is different than other Hormone positive cancers where they want the tumor removed first. Immunotherapy (Pembro) continues after surgery. Since I had surgery 12/9 and a smaller tumor was still there with active cancer, I will have to take oral chemo drug for 8 rounds of 3 weeks with pembro. As the combination of those two reduce the reoccurrence by half. I was negative for BRCA and other genetic markers, no family history, and opted for double mastectomy to see if I can avoid radiation. I hear from radiologist 12/29.

Look up Keynote 522 study if you want to see a standard of care many use to treat TNBC. Pembro is a key part in the 65% complete result response, meaning tumor is dead by time you have surgery. This gives you teh best outcome for reoccurance which is highest in the first three years.