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Estradiol levels with AI

Breast Cancer | Last Active: Feb 27 5:02pm | Replies (35)

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@anjalima

Tamoxifen suppresses estrogen without affecting bone integrity.

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Replies to "Tamoxifen suppresses estrogen without affecting bone integrity."

Generally, we are told that Tamoxifen does not suppress estrogen. It affects estrogen receptors, not the actual estrogen level in the body.
https://www.webmd.com/breast-cancer/guide/tamoxifen-for-breast-cancer-treatment-and-prevention
Does tamoxifen reduce estrogen?
"It blocks estrogen from working on cancer cells that are sensitive to the hormone. "

Though it's a little more complicated than that:
https://pubmed.ncbi.nlm.nih.gov/7214366/