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Anyone tapered off Effexor and used Prozac as a bridge?

Depression & Anxiety | Last Active: Feb 17 6:33am | Replies (73)
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@ruth3

I tried weaning from 112.5 Effexor to 75 as advised by a new psychiatrist who thinks I should never have been on it, but this was hell.

She now advises change directly to cymbalta 60mg and cut that down to 40 then 20 and off, has anyone success with this? It doesn’t have a long half life either. I go through daily withdrawals on Effexor as is Interdose, fast metaboliser. Thanks

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Replies to "I tried weaning from 112.5 Effexor to 75 as advised by a new psychiatrist who thinks..."
Teresa, Volunteer Mentor | @hopeful33250 | Dec 30, 2022

Hello @ruth3,

Weaning off Effexor, or any other antidepressant, can be a challenge. Unfortunately, we all react to this process differently, so it is hard to make any hard/fast rules. As you said, you are a "fast metabolizer" so the way you adjust to changes in meds might be entirely different than that of another person.

When I was taking Effexor, I was taking the smallest amount that could be prescribed. As I recall, it was just 25 mg and then switched to the smallest dosage of Cymbalta (perhaps 25 mg of that as well). You might also get a second opinion, from another psychiatrist, if you are still having problems.

Pharmacists are another very good resource. They can be very helpful in dealing with meds, after all, that is all that pharmacists work with! Do you know an experienced pharmacist who might be able to work with you on this?

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