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Estradiol levels with AI

Breast Cancer | Last Active: Feb 27 5:02pm | Replies (35)

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@anjalima

I’m in agreement with you and I am grateful to have this med available to me; I am counting on it to be of great value for my 98/99% ER+. I feel safer taking it. What you say stands to reason and makes perfect sense. That said, the medical and research establishment is looking into lowest possible dose/effectiveness ratio. They mention the reason is because side effects account for significant non-compliance. This does make one wonder what is under consideration because, as you say, the side effects are BECAUSE of estrogen reduction… which is what is needed for treatment.

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Replies to "I’m in agreement with you and I am grateful to have this med available to me;..."

It is a mystery! And it is a mystery why the dose is set where it is when the Femara drug info says 20% of that dose is effective.

I do wonder if there is some other mechanism in the medications that causes side effects, besides estrogen suppression. My doc didn't seem to think so.